All cables can stay connected to the unit while in the RAM cradle. The Garmin nuvi 2xxW Series, including the nuvi 205W, nuvi 255W, nuvi 200W, nuvi 250W and nuvi 260W WILL NOT fit this cradle. These units require the RAM-HOL-GA25 RAM Mount Cradle for the Garmin nuvi 2xxW and nuvi 2x5W Series. The cradle includes a set of two nuts and bolts to connect the cradle to any of the RAM compatible mounts.